Anti oxidants

Alpha lipoic acid, with purity levels surpassing 98%, acts as a powerful anti-aging agent by efficiently neutralizing free radicals through antioxidation. Its exceptional stability is attributed to its R/S (racemix) type characteristics. A comparison of oxidation and antioxidation agents underscores the effectiveness of alpha lipoic acid.

Usage: Ideal for anti-aging products intended to neutralize free radicals. Suitable for integration into serums, lotions, or creams.

Mixing method: Blend with oil, propylene glycol, or an emulsifier, while avoiding exposure to temperatures exceeding 40 degrees.

Recommended usage Percentage: 0.3-1.5% (Commence with a concentration of 0.3-0.5%, as ALA may potentially induce skin irritation).

Product characteristics: Manifests as a yellow powder.

Solubility: Capable of dissolving in oil, Propylene Glycol, and various types of Glycol.

Storage: Store in the refrigerator, ensuring the bottle is securely sealed and shielded from sunlight or heat. The product retains its quality for at least 4 years.

INCI: A. Alpha Lipoic Acid or Thioctic Acid.

Ascorbic acid, also known as vitamin C, is a naturally occurring organic compound with powerful antioxidant properties. It plays a crucial role in maintaining healthy skin, supporting the immune system, and promoting overall health. Ascorbic acid is widely used in cosmetics, personal care, and dietary supplements for its beneficial effects on skin health and its ability to boost immunity.

• Antioxidant Properties: Ascorbic acid helps neutralize free radicals, which can damage cells and contribute to aging and disease.
• Collagen Synthesis: It plays a role in the synthesis of collagen, a protein essential for healthy skin, hair, and connective tissues.
• Immune Support: Ascorbic acid is known to boost the immune system, aiding in the prevention and treatment of infections.
• Skin Brightening: It can reduce hyperpigmentation and even out skin tone, making it popular in skincare products.
• Wound Healing: Ascorbic acid supports the healing of wounds by promoting collagen production.

Common Uses of Ascorbic Acid

Skincare Products

Ascorbic acid is commonly used in skincare products for its antioxidant and skin-brightening properties. It is often found in:

• Serums and Creams: To reduce the appearance of fine lines and wrinkles, typically used at 5–20%
• Brightening Products: To lighten hyperpigmentation and even out skin tone
• Anti-Aging Products: To improve skin texture and reduce signs of aging

Dietary Supplements

Ascorbic acid is used in dietary supplements to provide vitamin C, which is essential for overall health. Common applications include:

• Vitamin C Tablets and Capsules: To boost the immune system, typically used at 50–1000 mg per dose
• Effervescent Tablets: To provide a fast-dissolving source of vitamin C

Food and Beverages

Ascorbic acid is also used in the food industry as an antioxidant and preservative. Common applications include:

• Fruit Juices and Drinks: To prevent oxidation and extend shelf life
• Baked Goods: To maintain freshness and improve texture

Product Specifications

• INCI Name: Ascorbic Acid
• CAS No: 50-81-7
• Product Type: Organic compound, antioxidant
• Usage: Skincare, dietary supplements, food and beverages
• Purity: Typically 95–99%
• Shelf Life: 2 years or more, depending on storage conditions

Storage and Handling

Store ascorbic acid in a cool, dry place, in a sealed container to prevent contamination and moisture absorption. Keep it away from direct sunlight and heat to maintain its stability and potency.

Our premium Azelaic Acid is the perfect addition to your arsenal of potent ingredients. Unleash the true potential of Azelaic Acid in your formulations and witness the unparalleled benefits it offers for achieving flawless, radiant skin.

Benefits:

1. A Marvel of Brightening: As a formulator, you'll appreciate Azelaic Acid's remarkable ability to fade dark spots, hyperpigmentation, and post-inflammatory marks. Enhance your brightening formulations and give your customers a luminous complexion they'll adore.

2. Gentle Exfoliation: Azelaic Acid gently exfoliates the skin's surface, promoting the natural shedding of dead skin cells. This ensures a smoother and more even skin texture, making it ideal for formulations catering to all skin types.

3. Acne Control Expertise: Formulate products that effectively target acne-prone skin. Azelaic Acid's anti-inflammatory and antimicrobial properties help combat acne-causing bacteria, reducing blemishes and preventing future breakouts.

4. Redness Relief: Your formulations can now address redness and irritation, as Azelaic Acid soothes inflamed skin, calming redness, and promoting a more balanced complexion.

5. Antioxidant Powerhouse: Elevate your antioxidant-rich products with Azelaic Acid's ability to neutralize free radicals. Shield your customers' skin from environmental stressors and support their skin's overall health.

How to Use:

As a formulator, you play a crucial role in ensuring the successful integration of Azelaic Acid into your formulations. Follow these guidelines for optimal results:

1. Recommended Concentration: Utilize Azelaic Acid at concentrations between 5% to 10% for its potent yet gentle effects on the skin.

2. pH Balancing Act: Maintain a pH level between 3.5 to 5.0 in your formulations to ensure Azelaic Acid remains stable and effective.

3. Patch Testing: Prior to releasing your formulations, conduct comprehensive patch tests to ensure compatibility and minimize the risk of adverse reactions.

4. Versatile Formulations: Azelaic Acid can be incorporated into various skincare products, including serums, creams, lotions, and spot treatments. Tailor the concentration based on the product's purpose and target audience.

5. Clear Usage Instructions: On the product labels, provide clear usage instructions for customers, advising them to apply your Azelaic Acid-infused product once or twice daily, depending on the product's formulation.

Dosage and Dissolving:

To achieve the recommended concentration, dissolve Azelaic Acid powder in a water-based solvent, such as propylene glycol or glycerin. Aim for a 5% to 10% concentration and ensure complete dissolution before incorporating it into your formulation.

With Azelaic Acid as your secret weapon, you can create groundbreaking skincare formulations that elevate your brand and satisfy your customers' desires for flawless and radiant skin.

Ingredients

• Caffeine

Warning

Concentrated caffeine powder should be stored away from areas where food is prepared to prevent accidental ingestion. Consumption of caffeine powder can lead to heart failure.

Our caffeine powder is a synthetic, high-purity form designed for cosmetic use.

Solubility

• Water Soluble

Appearance

• White Powder

Benefits

• Increases cellular energy
• Can penetrate the skin
• May aid in removing damaged skin

Recommendations

Caffeine may be beneficial for anti-aging and slimming applications.

Applications

Studies have used caffeine in skincare at doses of up to 5%, but we recommend between 0.1-0.5% in topical products. High concentrations can dehydrate the skin, reducing the benefits of caffeine.

Notes on Dermal Penetration

Caffeine can penetrate the skin, with clinical trials showing penetration rates into the bloodstream ranging from 2-10% of the applied dose. The absorption rate depends on the base formula, the concentration used, and the application site. Follicular delivery is efficient, which is why caffeine is often added to hair care products.

Cautions

• Not suitable for products intended for children.
• Exercise caution during pregnancy; caffeine levels should be monitored to ensure they remain within recommended guidelines.

Dose Rate

The recommended dose is between 0.1-0.5%.

Dry vitamin A acetate is a stable, powdered form of vitamin A, typically used in dietary supplements, food fortification, and personal care products. It is valued for its high stability and ease of handling compared to liquid forms of vitamin A. Vitamin A acetate, also known as retinyl acetate, is a derivative of vitamin A, essential for vision, immune function, and skin health.

Benefits of Dry Vitamin A Acetate

• Stability: Dry vitamin A acetate is stable and can be stored for extended periods without significant degradation.
• Ease of Handling: Its powdered form makes it easy to blend into dietary supplements, food products, and cosmetics.
• Source of Vitamin A: Vitamin A is crucial for healthy vision, immune system function, and cell growth.
• Skin Health: Vitamin A acetate is used in skincare products for its anti-aging and skin-regenerating properties.
• Immune Support: It helps maintain a healthy immune system by supporting white blood cell production.

Common Uses of Dry Vitamin A Acetate

Dietary Supplements

Dry vitamin A acetate is used in dietary supplements to provide a stable source of vitamin A. Common applications and recommended usage percentages include:

• Vitamin A Capsules and Tablets: To deliver vitamin A, typically used at 1000–5000 IU per dose
• Multivitamins: As part of a balanced mix of vitamins and minerals

Food Fortification

Dry vitamin A acetate is used in the food industry to fortify products with vitamin A. Common applications include:

• Breakfast Cereals: To provide additional vitamins, usually at 200–1000 IU per serving
• Dairy Products: To fortify milk, butter, and other dairy items with vitamin A

Personal Care and Cosmetics

Dry vitamin A acetate is used in skincare products for its anti-aging and regenerative properties. It is commonly found in:

• Anti-Aging Creams and Lotions: To promote cell regeneration and reduce the appearance of wrinkles, typically used at 0.1–1%
• Moisturizers: To improve skin texture and elasticity

Product Specifications

• INCI Name: Retinyl Acetate
• CAS No: 127-47-9
• Product Type: Vitamin A derivative
• Usage: Dietary supplements, food fortification, skincare, cosmetics
• Purity: Typically 95–99%
• Shelf Life: 2 years or more, depending on storage conditions

Storage and Handling

Store dry vitamin A acetate in a cool, dry place, in a sealed container to prevent contamination and moisture absorption. Keep it away from direct sunlight and heat to maintain its stability and potency.

Ferulic acid is a natural antioxidant found in various plant sources, including fruits, vegetables, grains, and seeds. It belongs to the class of hydroxycinnamic acids and has garnered significant interest for its antioxidant, anti-inflammatory, and potential anti-aging properties. Ferulic acid is commonly used in cosmetics and skincare products to protect against free radicals, enhance the stability of other antioxidants, and support skin health.

Characteristics of Ferulic Acid

• Chemical Formula: C10H10O4
• Appearance: White to yellowish powder or crystalline solid
• Odor: Mild or odorless
• Solubility: Soluble in alcohol, slightly soluble in water
• Source: Naturally found in plant cell walls; can be synthetically produced

Benefits of Ferulic Acid

• Antioxidant Properties: Ferulic acid helps neutralize free radicals, reducing oxidative stress and protecting skin from damage.
• Stabilization of Other Antioxidants: It can enhance the stability and effectiveness of other antioxidants, such as vitamin C and vitamin E.
• Anti-Aging Effects: Ferulic acid's antioxidant properties can help reduce the appearance of fine lines and wrinkles by protecting skin from environmental stressors.
• Anti-Inflammatory Properties: It has anti-inflammatory effects, which may help calm irritated skin.
• Skin Protection: Ferulic acid can provide some level of UV protection, aiding in the prevention of UV-induced skin damage.

Common Uses of Ferulic Acid

Skincare Products

Ferulic acid is widely used in skincare products for its antioxidant and anti-aging properties. Common applications and recommended usage percentages include:

• Serums: To provide antioxidant benefits and boost the stability of other antioxidants, typically used at 0.5–2%.
• Anti-Aging Products: To reduce the appearance of fine lines and wrinkles and promote youthful skin.
• Sunscreens: To enhance UV protection and provide additional antioxidant support.

Cosmetics

Ferulic acid is also used in cosmetic products for its stabilizing and protective properties. It is often found in:

• Foundations: To provide antioxidant benefits and improve skin health.
• BB Creams and CC Creams: To add antioxidant properties and improve product stability.

Product Specifications

• Chemical Formula: C10H10O4
• CAS No: 537-98-4
• Product Type: Antioxidant
• Usage: Skincare, cosmetics
• Purity: Typically 95–99%
• Shelf Life: 2 years or more, depending on storage conditions

Storage and Handling

Store ferulic acid in a cool, dry place, in a sealed container to prevent contamination and moisture absorption. Keep it away from direct sunlight and heat to maintain its quality and stability.

L-Glutathione is a naturally occurring tripeptide composed of three amino acids: glutamate, cysteine, and glycine. It is a powerful antioxidant found in cells throughout the body and plays a crucial role in protecting cells from oxidative stress, detoxifying harmful substances, and supporting the immune system. L-Glutathione is commonly used in cosmetics and skincare products for its skin-brightening and anti-aging properties.

Benefits of L-Glutathione

• Antioxidant Properties: L-Glutathione helps neutralize free radicals, protecting cells from oxidative damage and promoting cell health.
• Skin Brightening: It is used in skincare products for its ability to reduce hyperpigmentation and even out skin tone.
• Detoxification: L-Glutathione aids in detoxifying harmful substances in the body, supporting liver function.
• Anti-Aging: It can help reduce the signs of aging by protecting cells from damage and promoting cellular repair.
• Immune Support: L-Glutathione supports the immune system by enhancing the activity of white blood cells.

Common Uses of L-Glutathione

Skincare Products

L-Glutathione is commonly used in skincare products for its antioxidant and skin-brightening properties. Common applications and recommended usage percentages include:

• Skin Brightening Creams: To reduce hyperpigmentation and even out skin tone, typically used at 0.5–2%.
• Anti-Aging Serums: To reduce signs of aging and promote a youthful appearance.
• Face Masks: To provide a boost of antioxidants and brighten the skin.

Dietary Supplements

L-Glutathione is also used in dietary supplements for its detoxifying and immune-supporting properties. Common applications include:

• Antioxidant Supplements: To boost the body's natural antioxidant levels.
• Detoxification Support: To aid in the body's natural detoxification processes.

Product Specifications

• Chemical Formula: C10H17N3O6S
• CAS No: 70-18-8
• Product Type: Tripeptide
• Usage: Skincare, dietary supplements
• Purity: Typically 95–99%
• Shelf Life: 2 years or more, depending on storage conditions

Storage and Handling

Store L-Glutathione in a cool, dry place, in a sealed container to prevent contamination and moisture absorption. Keep it away from direct sunlight to maintain its quality and stability.

Vitamin C, 100% L-Ascorbic Acid, FCC, Ultrafine powder, is a water-soluble antioxidant with exceptional properties. Vitamin C, or L-ascorbic acid, is a powerful naturally occurring antioxidant that plays a crucial role in preventing dry skin, reducing wrinkles, promoting collagen synthesis, and facilitating skin regeneration. Ascorbate is present in all layers of the skin, with a higher concentration in the epidermis than the dermis. However, exposure to UV light can deplete cutaneous tissue stores of ascorbate by about two-thirds.

Biochemically, the body relies on ascorbate in the collagen biosynthetic pathway, where it serves as a cofactor for two enzymes, lysyl and prolyl hydroxylases. These enzymes, dependent on iron, benefit from Vitamin C's ability to prevent iron oxidation, ensuring the sustained activity of hydroxylases and thereby maintaining collagen production.

The topical application of Vitamin C has demonstrated efficacy in reducing the appearance of fine lines and wrinkles, primarily through mechanisms that support collagen production, resulting in improved skin texture. Additionally, Vitamin C has been proven to lessen the severity of sunburns and age spots, further showcasing its dermatological benefits.

INCI: Ascorbic Acid.

HOW TO USE: The difficulty for the cosmetic formulator is that L-Ascorbic Acid is very unstable in aqueous solutions, as it starts to oxidize immediately, gradually producing color changes (orange/brown shift) and a reduction in activity as it converts to dehydroascorbic acid. For cosmetic use, it is best stabilized in an anhydrous lipid or silicone base, although some have reported increased stability with the use of Ferulic Acid as part of aqueous formulations. This product is an ultrafine powder, ready to use in anhydrous formulations without further grinding. 

Typical usage Percentage: 1-20%
Appearance: Ultrafine white crystalline powder
pH (5% solution): 2.2 - 2.5
Solubility: Freely soluble in water (approx. 30g/100ml), sparingly soluble in absolute ethanol (2g/100ml), insoluble in fats and lipids.

CAS No.: 50-81-7

Radicals and reactive species are responsible for several mechanisms which trigger skin aging. They cause irreversible damage in cells and tissues, affecting organs too, so they are involved in a great number of diseases. In particular, Peroxynitrite, a powerful RNS (Reactive Nitrogen Species), exhibits a wide array of tissue-harmful effects, ranging from lipid peroxidation and DNA damage to inactivation of enzymes via protein oxidation and nitration. ROS (Reactive Oxygen Species) are free radicals generated from endogenous sources and also from external pro-oxidant stimuli.

Lipochroman®-6, is a remarkable molecule that can capture both nitrogen and oxygen radicals. In addition to this dual activity, Lipochroman®-6 is one of the most potent oxygen-radical scavengers. It is, therefore, a powerful active to prevent skin cell damage produced by several kinds of radicals and reactive species.

Oxidative stress is the imbalance between cellular production of free radical species and the ability of cells to eliminate them employing endogenous antioxidant defense mechanisms. This stress damages cells irreversibly. Cellular level studies of Lipochroman®-6 as compared to Resveratrol, Vitamin E and Ferulic Acid in cell viability assays indicate it increased cell viability by as much as 173% compared to these materials. The use of Lipochroman®-6 in cosmetic formulations can significantly reduce oxidative stress.

Cosmetic Benefits

• Double scavenging action: RNS and ROS
• Potent singlet oxygen scavenging activity
• Potent inhibitor or Peroxynitrite-induced lipid peroxidation
• Prevents skin cell damage induced by peroxynitrite and nitric oxide formation
• Internal photo-protection against UVA light by inhibiting ROS production
• Inhibits lipid peroxidation at low concentrations
• Avoids lipid peroxidation of essential oils in cosmetic formulations
• Protects human fibroblasts against oxidative stress

Cosmetic Applications

Lipochroman®-6 can be incorporated in oil-containing cosmetic formulations such as emulsions, gels, serum, etc., where premature skin aging avoidance is desired.

INCI: Dimethylmethoxy Chromanol

Important Note:  Lipochroman®-6 is a registered trademark of Lipotec and it cannot be referenced in your marketing literature without a signed Trademark Agreement with Lipotec.

Disclaimer
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

• Easily incorporated in cosmetic formulations dissolved in the appropriate solvent.
• It is recommended to add the product in the oily phase, at the final stage of the manufacturing process. Although it can be incorporated at a maximum temperature of 70°C (158°F), if formulated with oxidant agents the temperature should be lowered.

Recommended Usage Rate:0.01 - 0.05% (0.01 - 0.05gm per 100gm)
Appearance:Off white to beige crystalline powder
Solubility: Solubilize preferentially in aromatic solvents (C12-15 Alkyl Benzoate, Ethylhexyl Methoxycinnamate) and esters (Ethylhexyl Cocoate, Caprylic/Capric Triglycerides, etc.)
Solubility at Room Temperature
Ethylhexyl Methoxycinnamate 6.2%
C12-C15 Alkyl Benzoate 5.7%
Ethylhexyl Cocoate 2.7%

CAS#: 537-42-8

PteroWhite® 90%, derived from pterostilbene, a stable analogue of resveratrol found in red sandalwood, blueberries, and grapes, is a natural ingredient with properties that address localized hyper-pigmentation, brighten the skin, and function as an antioxidant, free radical scavenger, and anti-inflammatory agent. When used at 0.1% to 0.5% in water-based or emulsified skin products, it demonstrates its benefits.

PteroWhite® 90%, available as a 90% active powder, works by inhibiting melanin synthesis and tyrosinase production, promoting an even skin tone and reducing hyper-pigmentation. As a potent free radical scavenger and antioxidant, it effectively inhibits lipid peroxidation in cells, surpassing kojic acid or resveratrol in in vitro tests. Additionally, as an anti-inflammatory, it inhibits cytokines and COX-2 enzymes, proving to be more effective in vitro than resveratrol. Despite being water-insoluble (soluble in ethanol), it is safe and non-irritating when used up to 0.5%, and it should be added in the final phase of formulating at temperatures of 45ºC or 105ºF or lower.

Key Benefits

• Acts as an anti-oxidant and free radical scavenger
• Acts as an anti-inflammatory
• May have anti-fungal and anti-microbial properties
• Lightens skin by managing localized hyper-pigmentation
• Brightens skin and improves radiance by promoting a more uniform skin tone
• May act as a UV-B protectant Natural ingredient

Applications

• Anti-aging facial products, including sera, gels, light lotions, moisturizers, and masks
• Anti-inflammatory products for the face and body
• Skin lightening products for the face and body
• Sun-care and post sun-care products for the face and body

INCI: Pterocarpus Marsupium Bark Extract

Usage Percentage: 0.1% to 0.5% in the cool down phase of the product.
Appearance: White to cream colored powder
Solubility: Soluble in ethanol, 0.1g in 1g propylene glycol, 0.1g in 2g Polysorbate 20, and 0.1g in 1g in CCT oil when warmed to 40C

CAS No.: 1120360-11-3, 56-81-5, 7732-18-5

Vitamin C, 3-Glyceryl Ascorbate stands out as a vitamin C derivative known for its enhanced stability compared to powdered vitamin C alternatives. Unlike traditional vitamin C, this derivative maintains its color over time, resisting discoloration due to degradation. Importantly, being a stable product, it preserves the original color and content of a formulation. Vitamin C, 3-Glyceryl Ascorbate delivers the advantages of vitamin C in a formulation without the instability or degradation typically associated with traditional vitamin C options.

Key Benefits

• Behaves as an anti-oxidant to block UV damage and damage caused by stress, also brightens skin and improves skin regeneration.
• Suppresses melanin production for improvement of spots
• Conditions and moisturizes skin
• Enhances collagen production for improved elasticity

Cosmetic Applications

• gel-type formulations such as serums
  
• emulsions such as creams and lotions
• mildly acidic formulations 

INCI:  3-Glyceryl Ascorbate, Glycerin, Water

HOW TO USE 

• Add to the product at under 40°C (104°F)
• Incompatible with electrolytes (equal to or less than 2%), surfactants such as sodium lauryl sulfate (equal to or less than 30%), and electrophiles
• Recommended final pH of 2.0 to 5.0

Recommended Usage Percentage: 2% to 10%
Appearance: Light to medium amber liquid
Solubility: Soluble in water, propanediol, and glycerin. Insoluble in oils, esters, and silicones.
pH as supplied: 4.0 to 6.0
Specific gravity: 1.00 to 1.10
Country of Origin: USA
Raw Material Preserved with: Potassium Sorbate and Sodium Benzoate, Phytic Acid
Storage: Recommended at (4°- 8°C) 39°-45°F
Shelf Life:  15 Months from date of manufacture

CAS No. 7695-91-2

DL-Alpha Tocopheryl Acetate, also known as Vitamin E Acetate, is a stable form of Vitamin E widely utilized in cosmetic formulations for its skincare benefits. Vitamin E plays a crucial role in shielding cell membranes from damage caused by oxygen free radicals. It acts as a protective agent, helping to prevent premature aging of the skin induced by UV irradiation and lipid peroxidation.

Tocopherols and tocotrienols, the components of Vitamin E, efficiently scavenge lipid peroxyl free radicals, acting as chain-breaking antioxidants. This process is vital in limiting the propagation of lipid peroxidation in cell membranes. It's important to note that tocopherol may potentially act as a pro-oxidant in the absence of co-antioxidants like Vitamin C and under mild oxidative stress.

Natural Vitamin E can be prone to instability in skincare formulations, especially under UV irradiation. Alpha Tocopherol, the active form of Vitamin E, can rapidly convert to tocopheroxy radicals that consume other antioxidants. The use of Vitamin E Acetate, an ester of alpha tocopherol, helps overcome this limitation. Tocopheryl Acetate is biologically converted to vitamin E within the skin upon topical application. Studies indicate that the topical application of tocopherol and alpha tocopheryl acetate is more effective than dietary supplementation in increasing the vitamin E content of the skin.

Supported by numerous studies, Vitamin E Acetate has demonstrated the ability to increase enzyme activity in the skin, prevent free radical-induced skin damage, enhance the healing of surface wounds, and improve skin moisturization.

INCI: Tocopheryl Acetate

Recommended Usage Percentage: 0.5 - 5%

Material: DL-Alpha Tocopheryl Acetate 100%
Appearance: Clear yellow viscous oil
Origin: Synthetic
Country of Origin: China
Shelf Life: 24 months from date of manufacture